> Indice

- THE NEW REALITY

BREAKING THE CLONE BARRIER
Summary and comment from TIME MAGAZINE, March 29, 1999.
A Scottish scientist called Ian Wilmut has successfully conducted some amazing experiments in the field of embryology.
He has succeeded in getting a cell taken from an adult mammal to behave like one from a developing embryo.
Dolly at six months.Until now scientists thought that it was impossible to deprogram a differentiated mammalian cell. However, Wilmut took just one cell from adult female sheep and managed to clone a sheep called Dolly, in February, 1997. The experiment was simple and done with limited funding.
Wilmut's aim was not to cause an ethical earthquake but only to improve the productivity of farm animals. However, an American scientist, Richard Seed has said that he intends to clone humans for commercial purposes. He affirmed that cloning is "the first serious step toward becoming one with God."
Is he a Modern Frankenstein? Human Cloning! Is science fiction about to become a new reality?
In fact, the ethical foundations on which our society is based have been shaken by Wilmut's experiment. Some of the questions that have been raised are:
Could clones be used as slaves? Could clones be used as organ donors? Do they have a family? Are they made in God's image or in man's?
Ian Wilmut himself said it would be unacceptable to use his technique to create a human clone. Human cloning, he said, should be banned.

Cloning has been prohibited in most European countries, Australia and China but not completely in the USA. So perhaps a human clone will be produced secretly in the near future. Maybe the age of Frankenstein has arrived.

Are we waiting for the first human clone to be created secretly?

Someone, like Dr. Richard Rawlins, director of the in-vitro fertilization laboratory for the Rush Health System in Chicago says it is only a question of time before scientists announce that a human infant has been cloned. "In my opinion," he said, "all it takes right now is time, money and talent." The only question is who will do it first, he added. Perhaps the two fertility experts who recently announced that they wanted to clone a human, Dr. Panayiotis Zavos of the Andrology Institute in Lexington, and Dr. Severino Antinori, a fertility doctor in Rome. Perhaps it may be a relative unknown.

***
FIRST CLONED SHEEP DOLLY DIES AT 6
Dolly, the world's first cloned sheep, has been euthanized after being diagnosed with progressive lung disease, the Roslin Institute has said.
CCN.com - February 14, 2003



- GMO
WILL FRANKENFOOD FEED THE WORLD?
By Bill Gates
Summary and comment from TIME MAGAZINE, July 3, 2000.
Genetically Modified Organisms (GMO), now a reality and part of daily life in the U.S.A., have found strong opposition in Europe and in all those countries with long agrarian traditions. In wealthy European countries the concept of genetically altered food raises safety and ethical questions, although some people say it represents the possibility of a better life in the future, especially for the developing countries.
In the U.S.A. a third of the corn and more than half the soy-beans and cotton are the product of biotechnology. Yet, there are some problems to be faced. First of all, GMO must be subjected to testing. By 2050, the United Nations Organization estimates that the world population will probably reach 9 billion. Considering that cultivable land is declining and will decrease by half over the next 50 years, nearly 800 million people in the world will be undernourished, suffering from vitamin and iron deficiencies and other diseases caused by lack of food. Will biotechnology help to improve this situation?
American scientists are optimistic. They have already modified rice with beta-carotene which is converted by the body into vitamin A and iron and they are working on GM crops.
According to biologists GMO can improve farming productivity in places where food shortages are caused by crop damage because of pests such as the European corn borer which destroys 40 million tons of the world's corn crops. Yet there are those who say that GM pest-resistant crops might kill good insects as well as bad ones. However the biologists answer that these are unfounded fears. Scientists say that GM virus-resistant crops can reduce the damage of massive failure in staple crops in developing countries, as well as being able to reduce drought-tolerant seeds in regions where water shortages limit the amount of land under cultivation.
Scientists believe biotechnology could raise crop productivity in developing countries, as a consequence there are increasing collaborations between government agencies and private biotech firms.
WILL FRANKENFOOD FEED THE WORLD?
Biologists think that biotech promises to transform agriculture in many developing countries.

But, are we sure that GMO are not dangerous for our health? In Italy scepticism is greater especially among some political parties. In particular "the Greens" express a strong opposition to the introduction of GMO. They are fighting against GMO in Parliament claiming that we are not sure of the innocuous effects on human beings. They state that there is not enough proof to affirm that modified food is completely innocuous. Ordinary people think that GMO are dangerous.
Today, April 4th 2001, we can read in the newspaper that someone set a deposit of GM seeds on fire in Lodi.


-
GENETIC ENGINEERING

In the USA, micro-organisms, plants and animals, all results of genetic manipulations, have been patented since 1984. A bacterium and any other kind of animal or vegetable that has a gene added artificially in a laboratory, becomes exclusive property of the scientist that discovered it, exactly as happens to a song or a book. It is a real ethics revolution.
If the genetically modified organisms become private property of the creator, this means that life does not belong to nature but it is mankind's common good.
The risk of creating "monsters" through genetic modifications, and here the parallelism with Frankenstein's creature is very strong, halted to the European research . With an unexpected vote, the European Parliament rejected the "Frankenstein directive" which aimed at approving the possibility of making a patent for the results of genetic research. The investment for genetic research has been 400 million dollars and the whole project is called "Genome".
The "Genoma Project". The "Genoma Project" aims at knowing the 3.2 billion biochemical letters of DNA in a person's book of life that are the basis of the hundred thousand genes which constitute the human organism, enough to be able to recognize or substitute the faulty gene which causes hereditary diseases. Last summer the National Institutes of Health's Human Genoma Project announced the completion of a "working draft" of the human genome. The final copy-edit will probably take another two years.
Scientists'point of view. The Nobel Prize winner for medicine, Renato Dulbecco, considers that the veto from the European Parliament risks penalizing Europe in favour of the U.S. and Japan. Scientists affirm that genetic manipulation can have almost infinitive applications which go from medicine to agriculture and that it is not possible to stop the research. Rockfeller University biologists, for instance, have proved in principle, though only in mice, the futuristic concept known as therapeutic cloning. The idea is to take an ordinary skin cell from a patient, convert it into an embryo and use the embryo's cells to repair any desired tissue of the patient's body. The embryo is destroyed in the process.
Cloning.
Biology is undoubtedly one of the greatest protagonists of this final part of the century, but during the last years surprising scientific discoveries have brought polemics and discussions. The discovery of the DNA, the molecule responsible for the inheritance of genetic characteristics, recognized in the 1950s by Watson and Crick opened the way to the transformation of one organism into another of the same kind.
It is the process of cloning, a technique of producing a genetically identical duplicate of an organism by replacing the nucleus of an unfertilized ovum with the nucleus of a body cell from the organism. Are scientists like Victor Frankenstein going to "reproduce" life in a laboratory, creating human beings obtained after an accurate choice of elements?
Risks of genetic engineering.
Nowadays the risks of genetic engineering and the ethical implications that some experiments imply lead us to consider to what extent it is allowable.
And again the comparison with Frankenstein the scientist or the Modern Prometheus or the Modern Faust is surprising. What are the limits of human knowledge? An alarm has been spread with the experiments of some American scientists on the cloning of human embryos for the purpose of insemination. It seems that the American scientist, Richard Seed, is ready to double human beings using the same procedure adopted with the famous sheep Dolly. In the meanwhile we read in newspapers dated 5 May 2001 that modified babies have been born in an American laboratory at the St. Barnabas medical Center in New Jersey. The babies, born from a new method used to treat infertility, have genes from three different "parents" in their cells: the infertile mother, the father who fertilized the ovum and the fertile woman whose ovum was the source of the additional cytoplasm which made fertility possible.The researchers, among whom Dr. Jacques Cohen, assure that there are no risks for the 30 babies who have been born worldwide by means of this technique. They say that the added genes appear to have no effect on the babies who are healthy. Doubts remain and some scientists affirm that it is an alteration of human genes. Is it genetic manipulation? A positive answer comes from different parts including the American scientific community since cytoplasm contains mitochondria with their own genetic material which is transmitted to the baby. Some others, such as the Nobel Prize Renato Dulbecco, minimize the case affirming that it is not a matter of genetic manipulation. However such treatments which produce permanent genetic alterations might not have been approved without the federal committee's permission. But the work was privately funded and consequently needed no approvation. In Italy the Church and many politicians express alarm and anxiety about the case.
GM Food.
Genetic manipulation does not affect medicine only but agriculture, too.
After years of alarmistic tendencies, and disputes over the security of bio-nourishment and transgenical plants, the European Parliament has approved a directive. The new regulation expects more rigorous controls for the concessions of GMO cultivation. Firstly they cannot last more than 10 years, secondly there must be a public register locating the cultivations and verifying their impact on the environment and towards the biological and traditional agriculture. Lastly, and above all, the European Union establishes the obligation of a label. Many people would like to know what guarantee this label has. The packing of GM Food must be marked by an asterisk to signal the presence of GM ingredients so that the consumer can decide to buy it or not. According to the directive, the exporters of seeds and flour have not got the obligation to signal their products if they are GMO but it is the manufacturer that has to certify the presence of genetically modified ingredients in his produced food.


clonazione - genetica - organismi geneticamente modificati - mendel - OGM
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